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Department of Haematology
Notes

Full blood counts are performed on automated equipment and provide haemoglobin concentration, red cell indices, white cell count (with a differential count) and platelet count.
The presence of abnormal white cell and red cell morphology is flagged by the analysers.
Blood films may be inspected to confirm and interpret abnormalities identified by the cell counter, or to look for certain specific haematological abnormalities.
Grossly abnormal FBC results and abnormal blood films will be phoned through to the requestor.
There is no need to request a blood film to obtain a differential white count. It is, however, important that clinical details are provided to allow the laboratory to decide whether a blood film, in addition to the automated analysis, is required.
Under some circumstances a differential is not routinely performed, e.g. pre-op, post-op, antenatal and postnatal requests.
Full Blood Counts are performed at CGH and GRH
See also: Reticulocyte Count

The FBC comprises the following tests
Standard

Haemoglobin (Hb)
White Blood Count (WBC)
Platelet Count (Plt)
Red Cell Count (RBC)
Haematocrit (HCT)
Mean Cell Volume - Red cell (MCV)
Mean Cell Haemoglobin (MCH)

Differential White Cell Count (where applicable)

Neutrophils
Lymphocytes
Monocytes
Eosinophils
Basophils

And if appropriate

Blood Film

Sample Requirements
2ml or 4ml EDTA sample or a Paediatric 1ml EDTA sample.

 

Sample Storage and Retention

Pre analysis storage: do not store, send to laboratory within 4 hours.
Sample retention by lab: EDTA samples are retained for a minimum of 48 hours at 2-10°C
Transport of samples may affect sample viability, i.e. FBC results will degenerate if exposed to high temperatures, such as prolonged transportation in a hot car in summer.

This test can be added on to a previous request as long as there is sufficient sample remaining and the sample is less than 24 hours old.
Turnaround Times

Clinical emergency: 30 mins
Other urgent sample: 60 mins
Routine: within 2 hours

Reference Ranges


If references ranges are required for paediatric patients please contact the laboratory for these.

Parameter Patient Reference Range Units Haemoglobin Adult Male 130 - 180 g/L   Adult Female 115 - 165 g/L Red Cell Count Adult Male 4.50 - 6.50 x10^12/L   Adult Female 3.80 - 5.80 x10^12/L Haematocrit Adult Male 0.40 - 0.54 L/L   Adult Female 0.37 - 0.47 L/L Mean Cell Volume Adult 80 - 100 fL Mean Cell Haemoglobin Adult 27 - 32 pg White Cell Count Adult 3.6 - 11.0 x10^9/L Neutrophils Adult 1.8 - 7.5 x10^9/L Lymphocytes Adult 1.0 - 4.0 x10^9/L Monocytes Adult 0.2 - 0.8 x10^9/L Eosinophils Adult 0.1 - 0.4 x10^9/L Basophils Adult 0.02 - 0.10 x10^9/L Platelet Count Adult 140 - 400 x10^9/L

Section 1.10.33 of "de Finibus Bonorum et Malorum", written by Cicero in 45 BC
"At vero eos et accusamus et iusto odio dignissimos ducimus qui blanditiis praesentium voluptatum deleniti atque corrupti quos dolores et quas molestias excepturi sint occaecati cupiditate non provident, similique sunt in culpa qui officia deserunt mollitia animi, id est laborum et dolorum fuga. Et harum quidem rerum facilis est et expedita distinctio. Nam libero tempore, cum soluta nobis est eligendi optio cumque nihil impedit quo minus id quod maxime placeat facere possimus, omnis voluptas assumenda est, omnis dolor repellendus. Temporibus autem quibusdam et aut officiis debitis aut rerum necessitatibus saepe eveniet ut et voluptates repudiandae sint et molestiae non recusandae. Itaque earum rerum hic tenetur a sapiente delectus, ut aut reiciendis voluptatibus maiores alias consequatur aut perferendis doloribus asperiores repellat."
1914 translation by H. Rackham
"On the other hand, we denounce with righteous indignation and dislike men who are so beguiled and demoralized by the charms of pleasure of the moment, so blinded by desire, that they cannot foresee the pain and trouble that are bound to ensue; and equal blame belongs to those who fail in their duty through weakness of will, which is the same as saying through shrinking from toil and pain. These cases are perfectly simple and easy to distinguish. In a free hour, when our power of choice is untrammelled and when nothing prevents our being able to do what we like best, every pleasure is to be welcomed and every pain avoided. But in certain circumstances and owing to the claims of duty or the obligations of business it will frequently occur that pleasures have to be repudiated and annoyances accepted. The wise man therefore always holds in these matters to this principle of selection: he rejects pleasures to secure other greater pleasures, or else he endures pains to avoid worse pains."



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Live Cricket Score Updates, India vs England: Rain has delayed the toss as Virat Kohli-led India eye redemption against England in the second Test of their five-match series at Lord’s on Thursday.

Live Updates: The toss was delayed due to rain as India face England in the second Test at Lord’s. The visitors trail 1-0 after they were beaten in the first encounter at Edgbaston and Virat Kohli & Co will look to produce a better show on a ground where they have won just 2 out of their last 17 Test matches. Kohli will be banking on his top-order batsmen to fire after a disappointing show in the first Test and the visitors can opt for a second spin option in Kuldeep Yadav. For England, Ollie Pope will be making his debut with Moeen Ali possibly playing alongside Adil Rashid in the spin department.

 Hemoglobin is an iron-rich protein in red blood cells (RBCs).   The normal hemoglobin range for men is 13.5 to 17.5 gm/dL and 12 to 15.5 gm/dL for women. It is of utmost importance to maintain hemoglobin concentration.  
What you need to know:

What functions does hemoglobin perform in our bodies?
What causes low hemoglobin? 
Symptoms of low hemoglobin 
What are the foods that can increase hemoglobin level? 
Tips to increase your hemoglobin levels

What functions does hemoglobin perform in our bodies? 
Hemoglobin is vital for carrying oxygen from the lungs to tissues and organs. It also transports carbon dioxide from the tissues back to the lungs.
What causes low hemoglobin?

Some common causes of low hemoglobin are:

Substantial blood loss
Deficiency in iron, vitamin B, and folate
Kidney disease
Hypothyroidism
Thalassemia
Lung diseases
Excessive smoking

Any type of blood loss can cause anemia, including blood loss from surgery, heavy menstrual periods, and bleeding in the gastrointestinal tract. 
Symptoms of low hemoglobin
You can detect extremely low hemoglobin levels in your system in a few ways. They include

A fast or irregular heartbeat
Fatigue
Frequent or unexplained bruising
Shortness of breath
Liver and kidney disease
Pale skin and gums
Muscle weakness
Reoccurring headaches
Dizziness
Poor appetite
Anemia in severe cases

Elevated hemoglobin levels are associated with dehydration, heart failure, and chronic lung disease. In some conditions, the bone marrow may not produce enough RBCs, leading to cancers like leukemia, lymphoma, or tumors that spread from other parts of the body into the bone marrow.
What are the foods that can improve your hemoglobin levels?

It is essential to boost your food intake to raise your hemoglobin levels. Here are some foods to increase hemoglobin levels:

Iron-rich foods: Consume iron-rich foods like fish, meat, eggs, soy products, broccoli, green leafy vegetables that include spinach, fenugreek leaves, cauliflower, green peas, cabbage, green beans, nuts and seeds, and peanut butter, to increase your hemoglobin levels.
Vitamin A: It is pertinent to consume vitamin A foods to increase hemoglobin as they absorb more iron. Vitamin A and beta-carotene can help you there. Vitamin A is found in animal food sources, such as fish and liver. Beta-carotene is found in red, yellow, and orange fruits and vegetables.
Folate: Folate is a type of Vitamin B that plays an essential part in hemoglobin production. A shortage of folate can prevent the red blood cells from maturing, leading to anemia. Some good sources of folate include beef, rice, black-eyed peas, kidney beans, lettuce, and peanuts.
Foods rich in vitamin C: A combination of iron and vitamin C can prove to be beneficial. The latter is used for better absorption of iron. Foods rich in vitamin C include oranges, lemon, strawberries, papaya, bell peppers, broccoli, and tomatoes.
Fruits: It is also perfect to have fruits like beetroot, apple, watermelon, papaya, oranges, litchis, kiwis, strawberries, grapefruit, banana, and peach, which can boost hemoglobin levels. Plus, dry fruits, like dates, can increase the number of erythrocytes, thereby increasing hemoglobin levels. They contain iron, vitamin C, vitamin B complex, and folic acid, which helps in the formation of red blood cells. Raisins are also a rich source of iron and copper necessary to form red blood cells.

Avoid iron blockers: Foods that block your body’s ability to absorb iron, such as coffee, tea, alcohol, and aerated drinks, should be avoided.
Tips to increase your hemoglobin levels
Here are some tips to keep in mind to increase your hemoglobin levels:
Switch to brown rice: As a superfood, brown rice can help prevent various diseases related to cholesterol and the gastrointestinal system. It is rich in iron, containing 0.52 milligrams of iron for every 100 grams.
Enjoy dark chocolate: With over 80% of cocoa, dark chocolate naturally improves hemoglobin levels. Plus, it is loaded with minerals, nutrients and antioxidants.
Drink nettle tea: The spice nettle has also proven to be a good source of iron and vitamin B and C. They can also play a part in increasing hemoglobin levels.
 Exercise: Take up moderate to high-intensity exercise to help your body produce more hemoglobin to meet the oxygen demands of your body. 
Stay tuned to the Activ Living Community. Keep up to date with the latest health tips and trends through expert videos, podcasts, articles, and much more in nutrition, fitness, mindfulness, and lifestyle conditions like Asthma, Blood Pressure, Cholesterol, and Diabetes.
 You may also be interested in the following blogs: 

10 Vegetarian Foods That Are Rich In Iron
Want to Add Iron Rich Foods to Add in Your Diet? Check Out These Iron Rich Foods. 

Intent of this Success Criterion
The intent of this Success Criterion is to allow users to access the full content of a site without inducing seizures due to photosensitivity.
Individuals who have photosensitive seizure disorders can have a seizure triggered by content that flashes at certain frequencies for more than a few flashes. People are even more sensitive to red flashing than to other colors, so a special test is provided for saturated red flashing. These guidelines are based on guidelines for the broadcasting industry as adapted for computer screens, where content is viewed from a closer distance (using a larger angle of vision).
Flashing can be caused by the display, the computer rendering the image or by the content being rendered. The author has no control of the first two. They can be addressed by the design and speed of the display and computer. The intent of this criterion is to ensure that flicker that violates the flash thresholds is not caused by the content itself. For example, the content could contain a video clip or animated image of a series of strobe flashes, or close-ups of rapid-fire explosions.
This Success Criterion replaces a much more restrictive criterion in WCAG 1.0 that did not allow any flashing (even of a single pixel) within a broad frequency range (3 to 50 Hz). This Success Criterion is based on existing specifications in use in the UK and by others for television broadcast and has been adapted for computer display viewing. The 1024 x 768 screen is used as the reference screen resolution for the evaluation. The 341 x 256 pixel block represents a 10 degree viewport at a typical viewing distance. (The 10 degree field is taken from the original specifications and represents the central vision portion of the eye, where people are most susceptible to photo stimuli.)
The combined area of flashes occurring concurrently and contiguously means the total area that is actually flashing at the same time. It is calculated by adding up the contiguous area that is flashing simultaneously within any 10 degree angle of view.
 
Ref: https://www.w3.org/TR/UNDERSTANDING-WCAG20/seizure-does-not-violate.html
 

Types of kidney stones

Calcium stones are the most common type of kidney stones. They are usually made of calcium and oxalate (a natural chemical found in most foods), but are sometimes made of calcium and phosphate.
Uric acid stones form when your urine is often too acidic. Uric acid can form stones by itself or with calcium.
Struvite stones can happen when you have certain types of urinary tract infections in which bacteria make ammonia that builds up in your urine. Struvite stones are made of magnesium, ammonium and phosphate.
Cystine stones are made of a chemical that your body makes naturally, called cystine. Cystine stones are very rare, and happen in people who have a genetic disorder that causes cystine to leak from the kidneys into the urine.

What is Lorem Ipsum?
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What is Lorem Ipsum?
Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry's standard dummy text ever since the 1500s, when an unknown printer took a galley of type and scrambled it to make a type specimen book. It has survived not only five centuries, but also the leap into electronic typesetting, remaining essentially unchanged. It was popularised in the 1960s with the release of Letraset sheets containing Lorem Ipsum passages, and more recently with desktop publishing software like Aldus PageMaker including versions of Lorem Ipsum.


Why do we use it?
It is a long established fact that a reader will be distracted by the readable content of a page when looking at its layout. The point of using Lorem Ipsum is that it has a more-or-less normal distribution of letters, as opposed to using 'Content here, content here', making it look like readable English. Many desktop publishing packages and web page editors now use Lorem Ipsum as their default model text, and a search for 'lorem ipsum' will uncover many web sites still in their infancy. Various versions have evolved over the years, sometimes by accident, sometimes on purpose (injected humour and the like).