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Virology, together with all of biomedical sciences, is undergoing a revolution that can be encapsulated as a transition from reductionism to systems biology. This third edition of Viral Pathogenesis reflects this paradigm shift and the new perspective it brings to the field. Accordingly, this edition is organized in four different parts: (I) History and essentials of viral pathogenesis; (II) Systems-level approaches to viral pathogenesis; (III) Emergence and control of viral infections; and (IV) Past and future. Part I sets forth our knowledge based on long-established methods in pathology, virology, and adaptive immunity. This section provides the background for the rest of the book, which focuses on current and future methods and discoveries in viral pathogenesis.

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